Recent Advances in the Smiles Rearrangement: New Opportunities for Arylation
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Authors
Whalley, David M
Greaney, Michael F
Publication Date
2022Journal Title
SYNTHESIS-STUTTGART
ISSN
0039-7881
Publisher
Georg Thieme Verlag KG
Type
Article
This Version
AM
Metadata
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Whalley, D. M., & Greaney, M. F. (2022). Recent Advances in the Smiles Rearrangement: New Opportunities for Arylation. SYNTHESIS-STUTTGART https://doi.org/10.1055/a-1710-6289
Abstract
<jats:title>Abstract</jats:title><jats:p>The Smiles rearrangement has undergone a renaissance in recent years providing new avenues for non-canonical arylation techniques in both the radical and polar regimes. This short review will discuss recent applications of the reaction (from 2017 to late 2021), including its relevance to areas such as heterocycle synthesis and the functionalization of alkenes and alkynes as well as glimpses at new directions for the field.</jats:p><jats:p>1 Introduction</jats:p><jats:p>2 Polar Smiles Rearrangements</jats:p><jats:p>3 Radical Smiles: Alkene and Alkyne Functionalization</jats:p><jats:p>4 Radical Smiles: Rearrangements via C–X Bond Cleavage</jats:p><jats:p>5 Radical Smiles: Miscellaneous Rearrangements</jats:p><jats:p>6 Conclusions</jats:p>
Keywords
rearrangements, arylation, radicals, Smiles
Identifiers
External DOI: https://doi.org/10.1055/a-1710-6289
This record's URL: https://www.repository.cam.ac.uk/handle/1810/331765
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