Global epidemiology of vasculitis.
Burns, Jane C
Nat Rev Rheumatol
Springer Science and Business Media LLC
MetadataShow full item record
Watts, R. A., Hatemi, G., Burns, J. C., & Mohammad, A. J. (2022). Global epidemiology of vasculitis.. Nat Rev Rheumatol, 18 (1), 22-34. https://doi.org/10.1038/s41584-021-00718-8
The many forms of vasculitis are characterized by inflammation of blood vessels, leading to potentially long-term sequelae including vision loss, aneurysm formation and kidney failure. Accurate estimation of the incidence and prevalence has been hampered by the absence of reliable diagnostic criteria and the rarity of these conditions; however, much progress has been made over the past two decades, although data are still lacking from many parts of the world including the Indian subcontinent, China, Africa and South America. Giant cell arteritis occurs in those aged 50 years and over and seems to mainly affect persons of northern European ancestry, whereas Takayasu arteritis occurs mainly in those aged under 40 years. By contrast, Kawasaki disease mainly occurs in children aged under 5 years and is most common in children of Asian ancestry, and IgA vasculitis occurs in children and adolescents. Although much less common than giant cell arteritis, the different forms of antineutrophil cytoplasmic antibody-associated vasculitis are being increasingly recognized in most populations and occur more frequently with increasing age. Behçet syndrome occurs most commonly along the ancient silk road between Europe and China. Much work needs to be done to better understand the influence of ethnicity, geographical location, environment and social factors on the development of vasculitis.
Global Health, Humans, Vasculitis
External DOI: https://doi.org/10.1038/s41584-021-00718-8
This record's URL: https://www.repository.cam.ac.uk/handle/1810/332506
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