The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-Ischemic Heart Failure in Mice.
Published version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Yura, Yoshimitsu
Katanasaka, Yasufumi
Min, Kyung-Duk
Abstract
[Figure: see text].
Description
Keywords
CRISPR-Cas Systems, DNA damage, cardiotoxicity, clonal hematopoiesis, heart failure, inflammasome, macrophages, Angiotensin II, Animals, Clonal Hematopoiesis, DNA Damage, Gain of Function Mutation, Heart Failure, Hematopoietic Stem Cells, Inflammasomes, Interleukin-18, Interleukin-1beta, Macrophages, Male, Mice, Mice, Inbred C57BL, NLR Family, Pyrin Domain-Containing 3 Protein, Protein Phosphatase 2C
Journal Title
Circ Res
Conference Name
Journal ISSN
0009-7330
1524-4571
1524-4571
Volume Title
129
Publisher
Ovid Technologies (Wolters Kluwer Health)
Publisher DOI
Sponsorship
Medical Research Council (MC_PC_17230)