Imaging response assessment for CNS germ cell tumours: consensus recommendations from the European Society for Paediatric Oncology Brain Tumour Group and North American Children's Oncology Group.
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Authors
Morana, Giovanni
Shaw, Dennis
MacDonald, Shannon M
Alapetite, Claire
Ajithkumar, Thankamma
Bhatia, Aashim
Brisse, Hervé
Jaimes, Camilo
Czech, Thomas
Dhall, Girish
Fangusaro, Jason
Faure-Conter, Cecile
Fouladi, Maryam
Hargrave, Darren
Harreld, Julie H
Mitra, Dipayan
Nicholson, James C
Souweidane, Mark
Timmermann, Beate
Calaminus, Gabriele
Bartels, Ute
Bison, Brigitte
Murray, Matthew J
Publication Date
2022-05Journal Title
Lancet Oncol
ISSN
1470-2045
Publisher
Elsevier BV
Type
Article
This Version
AM
Metadata
Show full item recordCitation
Morana, G., Shaw, D., MacDonald, S. M., Alapetite, C., Ajithkumar, T., Bhatia, A., Brisse, H., et al. (2022). Imaging response assessment for CNS germ cell tumours: consensus recommendations from the European Society for Paediatric Oncology Brain Tumour Group and North American Children's Oncology Group.. Lancet Oncol https://doi.org/10.1016/S1470-2045(22)00063-8
Abstract
Homogeneous and common objective disease assessments and standardised response criteria are important for better international clinical trials for CNS germ cell tumours. Currently, European protocols differ from those of North America (the USA and Canada) in terms of criteria to assess radiological disease response. An international working group of the European Society for Paediatric Oncology Brain Tumour Group and North American Children's Oncology Group was therefore established to review existing literature and current practices, identify major challenges regarding imaging assessment, and develop consensus recommendations for imaging response assessment for patients with CNS germ cell tumours. New clinical imaging standards were defined for the most common sites of CNS germ cell tumour and for the definition of locoregional extension. These new standards will allow the evaluation of response to therapy in patients with CNS germ cell tumours to be more consistent, and facilitate direct comparison of treatment outcomes across international studies.
Sponsorship
German Childhood Cancer Association (Deutsche Kinderkrebsstiftung).
Identifiers
External DOI: https://doi.org/10.1016/S1470-2045(22)00063-8
This record's URL: https://www.repository.cam.ac.uk/handle/1810/332803
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
Licence URL: https://creativecommons.org/licenses/by-nc-nd/4.0/
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