Unwelcome memento mori or best clinical practice? Community end of life anticipatory medication prescribing practice: A mixed methods observational study.
MetadataShow full item record
Bowers, B., Pollock, K., & Barclay, S. (2022). Unwelcome memento mori or best clinical practice? Community end of life anticipatory medication prescribing practice: A mixed methods observational study.. Palliat Med, 36 (1), 95-104. https://doi.org/10.1177/02692163211043382
Funder: RCN Foundation; Grant(s): RCN Foundation Professional Bursary Scheme: BB [gr
BACKGROUND: Anticipatory medications are injectable drugs prescribed ahead of possible need for administration if distressing symptoms arise in the final days of life. Little is known about how they are prescribed in primary care. AIM: To investigate the frequency, timing and recorded circumstances of anticipatory medications prescribing for patients living at home and in residential care. DESIGN: Retrospective mixed methods observational study using General Practitioner and community nursing clinical records. SETTING/PARTICIPANTS: 329 deceased adult patients registered with Eleven General Practitioner practices and two associated community nursing services in two English counties (30 most recent deaths per practice). Patients died from any cause except trauma, sudden death or suicide, between 4 March 2017 and 25 September 2019. RESULTS: Anticipatory medications were prescribed for 167/329 (50.8%) of the deceased patients, between 0 and 1212 days before death (median 17 days). The likelihood of prescribing was significantly higher for patients with a recorded preferred place of death (odds ratio [OR] 34; 95% CI 15-77; p < 0.001) and specialist palliative care involvement (OR 7; 95% CI 3-19; p < 0.001). For 66.5% of patients (111/167) anticipatory medications were recorded as being prescribed as part of a single end-of-life planning intervention. CONCLUSION: The variability in the timing of prescriptions highlights the challenges in diagnosing the end-of-life phase and the potential risks of prescribing far in advance of possible need. Patient and family views and experiences of anticipatory medication care, and their preferences for involvement in prescribing decision-making, warrant urgent investigation.
Original Articles, Anticipatory prescribing, anticipatory medications, palliative medicine kit, terminal care, palliative care, mixed methods, end of life care, home palliative care, community nursing, general practice
National Institute for Health Research (NIHR) School for Primary Care Research; NIHR Applied Research Collaboration East of England (ARC EoE) programme
National Institute for Health Research (NIHR) (via University of Oxford) (Capacity Building Award 9)
National Institute for Health Research (NIHR) (SPCR-146)
External DOI: https://doi.org/10.1177/02692163211043382
This record's URL: https://www.repository.cam.ac.uk/handle/1810/333359