Research data supporting "Dissociable and Paradoxical Roles of Rat Medial and Lateral Orbitofrontal Cortex in Visual Serial Reversal Learning"
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Hervig, Mona El-Sayed
Olesen, Sarah F
Robbins, Trevor W
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Hervig, M. E., Fiddian, L., Piilgard, L., Bozic, T., Blanco-Pozo, M., Knudsen, C., Olesen, S. F., et al. (2022). Research data supporting "Dissociable and Paradoxical Roles of Rat Medial and Lateral Orbitofrontal Cortex in Visual Serial Reversal Learning" [Dataset]. https://doi.org/10.17863/CAM.81223
We investigated the effects of pharmacological inactivation of mOFC and lOFC on a deterministic serial visual reversal learning task for rats. For reference, we also targeted other areas previously implicated in reversal learning: prelimbic (PrL) and infralimbic (IL) prefrontal cortex, and basolateral amygdala (BLA). We also investigated the effect of lOFC and mOFC inactivatoin on visual discrimination (without a reversal component). Each .csv file corresponds to one experiment: reversal learning data from mOFC, lOFC, IL, PrL, BLA; novel visual discrimination data from mOFC, lOFC.
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amygdala, orbitofrontal cortex, prefrontal cortex, reversal learning, visual discrimination
Publication Reference: https://doi.org/10.1093/cercor/bhz144https://www.repository.cam.ac.uk/handle/1810/293800
This work was funded by a Wellcome Trust Senior Investigator Grant to TWR (104631/Z/14/Z), a Lundbeck Foundation Research Fellowship (R182-2014-2810 and R210-2015-2982 to MEH) and a BBSRC studentship (to LF).
Wellcome Trust (104631/Z/14/Z)
This record's DOI: https://doi.org/10.17863/CAM.81223
Attribution 4.0 International (CC BY 4.0)
Licence URL: https://creativecommons.org/licenses/by/4.0/