Research data supporting "Dissociable and Paradoxical Roles of Rat Medial and Lateral Orbitofrontal Cortex in Visual Serial Reversal Learning"


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Authors
Hervig, Mona El-Sayed 
Fiddian, Leanne 
Piilgard, Louise 
Bozic, Tadej 
Blanco-Pozo, Marta 
Description

We investigated the effects of pharmacological inactivation of mOFC and lOFC on a deterministic serial visual reversal learning task for rats. For reference, we also targeted other areas previously implicated in reversal learning: prelimbic (PrL) and infralimbic (IL) prefrontal cortex, and basolateral amygdala (BLA). We also investigated the effect of lOFC and mOFC inactivatoin on visual discrimination (without a reversal component).

Each .csv file corresponds to one experiment: reversal learning data from mOFC, lOFC, IL, PrL, BLA; novel visual discrimination data from mOFC, lOFC.

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Keywords
amygdala, orbitofrontal cortex, prefrontal cortex, reversal learning, visual discrimination
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Sponsorship
Wellcome Trust (104631/Z/14/Z)
This work was funded by a Wellcome Trust Senior Investigator Grant to TWR (104631/Z/14/Z), a Lundbeck Foundation Research Fellowship (R182-2014-2810 and R210-2015-2982 to MEH) and a BBSRC studentship (to LF).
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