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dc.contributor.authorTamborero, David
dc.contributor.authorDienstmann, Rodrigo
dc.contributor.authorRachid, Maan Haj
dc.contributor.authorBoekel, Jorrit
dc.contributor.authorLopez-Fernandez, Adria
dc.contributor.authorJonsson, Markus
dc.contributor.authorRazzak, Ali
dc.contributor.authorBraña, Irene
dc.contributor.authorDe Petris, Luigi
dc.contributor.authorYachnin, Jeffrey
dc.contributor.authorBaird, Richard
dc.contributor.authorLoriot, Yohann
dc.contributor.authorMassard, Christophe
dc.contributor.authorMartin-Romano, Patricia
dc.contributor.authorOpdam, Frans
dc.contributor.authorSchlenk, Richard F
dc.contributor.authorVernieri, Claudio
dc.contributor.authorMasucci, Michele
dc.contributor.authorVillalobos, Xenia
dc.contributor.authorChavarria, Elena
dc.contributor.authorCancer Core Europe consortium
dc.contributor.authorBalmaña, Judith
dc.contributor.authorApolone, Giovanni
dc.contributor.authorCaldas, Carlos
dc.contributor.authorBergh, Jonas
dc.contributor.authorErnberg, Ingemar
dc.contributor.authorFröhling, Stefan
dc.contributor.authorGarralda, Elena
dc.contributor.authorKarlsson, Claes
dc.contributor.authorTabernero, Josep
dc.contributor.authorVoest, Emile
dc.contributor.authorRodon, Jordi
dc.contributor.authorLehtiö, Janne
dc.date.accessioned2022-02-28T17:00:35Z
dc.date.available2022-02-28T17:00:35Z
dc.date.issued2022-02
dc.date.submitted2021-04-07
dc.identifier.issn2662-1347
dc.identifier.others43018-022-00332-x
dc.identifier.other332
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/334509
dc.description.abstractThere is a growing need for systems that efficiently support the work of medical teams at the precision-oncology point of care. Here, we present the implementation of the Molecular Tumor Board Portal (MTBP), an academic clinical decision support system developed under the umbrella of Cancer Core Europe that creates a unified legal, scientific and technological platform to share and harness next-generation sequencing data. Automating the interpretation and reporting of sequencing results decrease the need for time-consuming manual procedures that are prone to errors. The adoption of an expert-agreed process to systematically link tumor molecular profiles with clinical actions promotes consistent decision-making and structured data capture across the connected centers. The use of information-rich patient reports with interactive content facilitates collaborative discussion of complex cases during virtual molecular tumor board meetings. Overall, streamlined digital systems like the MTBP are crucial to better address the challenges brought by precision oncology and accelerate the use of emerging biomarkers.
dc.languageen
dc.publisherSpringer Science and Business Media LLC
dc.subjectTechnical Report
dc.subject/692/4028/67/69
dc.subject/692/4028/67/68
dc.subject/692/699/67
dc.subject/631/114
dc.subjecttechnical-report
dc.titleThe Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.
dc.typeArticle
dc.date.updated2022-02-28T17:00:34Z
prism.endingPage261
prism.issueIdentifier2
prism.publicationNameNat Cancer
prism.startingPage251
prism.volume3
dc.identifier.doi10.17863/CAM.81927
dcterms.dateAccepted2022-01-10
rioxxterms.versionofrecord10.1038/s43018-022-00332-x
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidTamborero, David [0000-0002-7218-2806]
dc.contributor.orcidLopez-Fernandez, Adria [0000-0002-2844-5998]
dc.contributor.orcidBaird, Richard [0000-0001-7071-6483]
dc.contributor.orcidBalmaña, Judith [0000-0002-0762-6415]
dc.contributor.orcidCaldas, Carlos [0000-0003-3547-1489]
dc.contributor.orcidBergh, Jonas [0000-0001-5526-1847]
dc.contributor.orcidErnberg, Ingemar [0000-0001-6518-1648]
dc.contributor.orcidFröhling, Stefan [0000-0001-7907-4595]
dc.contributor.orcidTabernero, Josep [0000-0002-2495-8139]
dc.contributor.orcidVoest, Emile [0000-0001-8249-9586]
dc.contributor.orcidLehtiö, Janne [0000-0002-8100-9562]
dc.identifier.eissn2662-1347
pubs.funder-project-idEuropean Commission Horizon 2020 (H2020) ERC (965397)
pubs.funder-project-idMedical Research Council (MR/P012442/1)
cam.issuedOnline2022-02-24


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