Long COVID-19 and Postural Orthostatic Tachycardia Syndrome- Is Dysautonomia to Be Blamed?
Authors
Chadda, Karan R
Blakey, Ellen E
Huang, Christopher L-H
Jeevaratnam, Kamalan
Publication Date
2022Journal Title
Front Cardiovasc Med
ISSN
2297-055X
Publisher
Frontiers Media SA
Volume
9
Language
en
Type
Article
This Version
VoR
Metadata
Show full item recordCitation
Chadda, K. R., Blakey, E. E., Huang, C. L., & Jeevaratnam, K. (2022). Long COVID-19 and Postural Orthostatic Tachycardia Syndrome- Is Dysautonomia to Be Blamed?. Front Cardiovasc Med, 9 https://doi.org/10.3389/fcvm.2022.860198
Abstract
While the increased arrhythmic tendency during acute COVID-19 infection is recognised, the long-term cardiac electrophysiological complications are less well known. There are a high number of patients reporting ongoing symptoms post-infection, termed long COVID. A recent hypothesis is that long COVID symptoms could be attributed to dysautonomia, defined as malfunction of the autonomic nervous system (ANS). The most prevalent cardiovascular dysautonomia amongst young people is postural orthostatic tachycardia syndrome (POTS). Numerous reports have described the development of POTS as part of long COVID. Possible underlying mechanisms, although not mutually exclusive or exhaustive, include hypovolaemia, neurotropism, inflammation and autoimmunity. Treatment options for POTS and other long COVID symptoms are currently limited. Future research studies should aim to elucidate the underlying mechanisms of dysautonomia to enable the development of targeted therapies. Furthermore, it is important to educate healthcare professionals to recognise complications and conditions arising from COVID-19, such as POTS, to allow prompt diagnosis and access to early treatment.
Keywords
Cardiovascular Medicine, long COVID, tachycardia, postural orthostatic tachycardia syndrome, dysautonomia, arrhythmia
Identifiers
External DOI: https://doi.org/10.3389/fcvm.2022.860198
This record's URL: https://www.repository.cam.ac.uk/handle/1810/335442
Rights
Licence:
http://creativecommons.org/licenses/by/4.0/
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