High-Refractive-Index Chip with Periodically Fine-Tuning Gratings for Tunable Virtual-Wavevector Spatial Frequency Shift Universal Super-Resolution Imaging.
Authors
Han, Yubing
Ye, Dehao
Zhang, Qianwei
Pang, Chenlei
Liu, Xiaowei
Shen, Weidong
Ma, Yaoguang
Kaminski, Clemens F
Liu, Xu
Publication Date
2022-03Journal Title
Adv Sci (Weinh)
ISSN
2198-3844
Publisher
Wiley
Volume
9
Issue
9
Language
en
Type
Article
This Version
AO
VoR
Metadata
Show full item recordCitation
Tang, M., Han, Y., Ye, D., Zhang, Q., Pang, C., Liu, X., Shen, W., et al. (2022). High-Refractive-Index Chip with Periodically Fine-Tuning Gratings for Tunable Virtual-Wavevector Spatial Frequency Shift Universal Super-Resolution Imaging.. Adv Sci (Weinh), 9 (9) https://doi.org/10.1002/advs.202103835
Description
Funder: Zhejiang University Education Foundation Global Partnership Fund
Funder: Open Foundation of the State Key Laboratory of Modern Optical Instrumentation
Funder: Zhejiang University Micro‐Nano Fabrication Center
Abstract
Continued research in fields such as materials science and biomedicine requires the development of a super-resolution imaging technique with a large field of view (FOV) and deep subwavelength resolution that is compatible with both fluorescent and nonfluorescent samples. Existing on-chip super-resolution methods exclusively focus on either fluorescent or nonfluorescent imaging, and, as such, there is an urgent requirement for a more general technique that is capable of both modes of imaging. In this study, to realize labeled and label-free super-resolution imaging on a single scalable photonic chip, a universal super-resolution imaging method based on the tunable virtual-wavevector spatial frequency shift (TVSFS) principle is introduced. Using this principle, imaging resolution can be improved more than threefold over the diffraction limit of a linear optical system. Here, diffractive units are fabricated on the chip's surface to provide wavevector-variable evanescent wave illumination, enabling tunable spatial frequency shifts in the Fourier space. A large FOV and resolutions of λ/4.7 and λ/7.1 were achieved for label-free and fluorescently labeled samples using a gallium phosphide (GaP) chip. With its large FOV, compatibility with different imaging modes, and monolithic integration, the proposed TVSFS chip may advance fields such as cell engineering, precision industry inspection, and chemical research.
Keywords
Research Article, Research Articles, field of view, label‐free, super‐resolution chips, tunable virtual‐wavevector spatial frequency shift
Sponsorship
National Natural Science Foundation of China (61822510, 61735017, 62020106002, 31901059, 62005250)
National Key Research and Development Program of China (2018YFE0119000)
Identifiers
advs3469
External DOI: https://doi.org/10.1002/advs.202103835
This record's URL: https://www.repository.cam.ac.uk/handle/1810/335606
Rights
Licence:
http://creativecommons.org/licenses/by/4.0/
Statistics
Total file downloads (since January 2020). For more information on metrics see the
IRUS guide.
Recommended or similar items
The current recommendation prototype on the Apollo Repository will be turned off on 03 February 2023. Although the pilot has been fruitful for both parties, the service provider IKVA is focusing on horizon scanning products and so the recommender service can no longer be supported. We recognise the importance of recommender services in supporting research discovery and are evaluating offerings from other service providers. If you would like to offer feedback on this decision please contact us on: support@repository.cam.ac.uk