HIV-1 Evolutionary Dynamics under Nonsuppressive Antiretroviral Therapy

Kemp, Steven; Charles, Oscar J; Derache, Anne; Smidt, Werner; Martin, Darren P; Iwuji, Collins; Adamson, John; Govender, Katya; de Oliveira, Tulio; Dabis, Francois; Pillay, Deenan; Goldstein, Richard A; Gupta, Ravindra

View / Open Files

Published version (PDF, 4Mb)

Authors

Kemp, Steven

Charles, Oscar J

Derache, Anne

Smidt, Werner

Martin, Darren P

Iwuji, Collins

Adamson, John

Publication Date

2022-04-21

Journal Title

mBio

ISSN

2150-7511

Publisher

American Society for Microbiology

Type

Article

This Version

VoR

Metadata

Show full item record

Citation

Kemp, S., Charles, O. J., Derache, A., Smidt, W., Martin, D. P., Iwuji, C., Adamson, J., et al. (2022). HIV-1 Evolutionary Dynamics under Nonsuppressive Antiretroviral Therapy. mBio https://doi.org/10.1128/mbio.00269-22

Abstract

HIV-1 infections are most commonly initiated with a single founder virus and are characterized by extensive inter- and intraparticipant genetic diversity. However, existing literature on HIV-1 intrahost population dynamics is largely limited to untreated infections, predominantly in subtype B-infected individuals.

Sponsorship

Wellcome Trust (108082/A/15/Z)

Identifiers

External DOI: https://doi.org/10.1128/mbio.00269-22

This record's URL: https://www.repository.cam.ac.uk/handle/1810/336482

Rights

Attribution 4.0 International

Licence URL: https://creativecommons.org/licenses/by/4.0/

Statistics

Total file downloads (since January 2020). For more information on metrics see the IRUS guide.

Except where otherwise noted, this item's licence is described as Attribution 4.0 International