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dc.contributor.authorJames, Emily
dc.contributor.authorMiranda, Roberto N
dc.contributor.authorTurner, Suzanne
dc.date.accessioned2022-05-12T02:30:31Z
dc.date.available2022-05-12T02:30:31Z
dc.date.issued2022-06
dc.identifier.issn2352-5878
dc.identifier.other35402679
dc.identifier.otherPMC8987598
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/337060
dc.description.abstractLymphomas of the breast are rare neoplasms that arise from breast lymphoid tissue and are characterised by neoplastic B or T cells. Breast lymphomas arising from B cells include, but are not limited to, diffuse large B cell lymphoma, follicular lymphoma, extra-nodal marginal zone lymphoma and Burkitt lymphoma. Anaplastic large cell lymphoma (ALCL) is of a T cell origin and both anaplastic lymphoma kinase (ALK)-positive and ALK-negative presentations have been noted in the breast. In addition, there is a more recently identified presentation of ALK-negative ALCL that arises around textured breast implants and is usually confined to a periprosthetic fibrous capsule. Here, we discuss the clinical presentations, histological and immunohistochemical features and treatment options for each type of primary breast lymphoma. We hope that this review will highlight the importance of the timely and accurate diagnosis of breast lymphoma in order to tailor the most appropriate treatment. We also wish to raise awareness of the breast implant-associated lymphomas, with the goal of stimulating work that will aid our understanding of their epidemiology and pathogenesis.
dc.languageeng
dc.publisherElsevier BV
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourcenlmid: 101680420
dc.sourceessn: 2352-5878
dc.subjectNon-hodgkin Lymphoma
dc.subjectBreast Implants
dc.subjectBreast Lymphoma
dc.subjectBia-alcl
dc.subjectBreast Implant Lymphoma
dc.titlePrimary Lymphomas of the Breast: A Review.
dc.typeArticle
dc.date.updated2022-05-12T02:30:31Z
prism.endingPage143
prism.publicationNameJPRAS Open
prism.startingPage127
prism.volume32
dc.identifier.doi10.17863/CAM.84483
dcterms.dateAccepted2022-01-10
rioxxterms.versionofrecord10.1016/j.jpra.2022.01.004
rioxxterms.versionVoR
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.contributor.orcidTurner, Suzanne [0000-0002-8439-4507]
dc.identifier.eissn2352-5878


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International