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dc.contributor.authorBashari, WA
dc.contributor.authorGillett, D
dc.contributor.authorMacFarlane, J
dc.contributor.authorPowlson, AS
dc.contributor.authorKolias, Angelos
dc.contributor.authorMannion, R
dc.contributor.authorScoffings, DJ
dc.contributor.authorMendichovszky, IA
dc.contributor.authorJones, J
dc.contributor.authorCheow, HK
dc.contributor.authorKoulouri, O
dc.contributor.authorGurnell, Mark
dc.date.accessioned2022-06-02T23:30:18Z
dc.date.available2022-06-02T23:30:18Z
dc.date.issued2022-06-06
dc.identifier.issn1386-341X
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/337694
dc.description.abstractManagement of Cushing's disease is informed by dedicated imaging of the sella and parasellar regions. Although magnetic resonance imaging (MRI) remains the investigation of choice, a significant proportion (30-50%) of corticotroph tumours are so small as to render MRI indeterminate or negative when using standard clinical sequences. In this context, alternative MR protocols [e.g. 3D gradient (recalled) echo, with acquisition of volumetric data] may allow detection of tumors that have not been previously visualized. The use of hybrid molecular imaging (e.g. 11C-methionine positron emission tomography coregistered with volumetric MRI) has also been proposed as an additional modality for localizing microadenomas.
dc.publisherSpringer Science and Business Media LLC
dc.rightsAll Rights Reserved
dc.rights.urihttp://www.rioxx.net/licenses/all-rights-reserved
dc.titleModern imaging in Cushing's disease.
dc.typeArticle
dc.publisher.departmentDepartment of Medicine
dc.date.updated2022-06-01T14:42:17Z
prism.publicationNamePituitary
dc.identifier.doi10.17863/CAM.85100
dcterms.dateAccepted2022-05-19
rioxxterms.versionofrecord10.1007/s11102-022-01236-w
rioxxterms.versionAM
dc.contributor.orcidKolias, Angelos [0000-0003-3992-0587]
dc.contributor.orcidGurnell, Mark [0000-0001-5745-6832]
dc.identifier.eissn1573-7403
rioxxterms.typeJournal Article/Review
pubs.funder-project-idNational Institute for Health Research (NIHRDH-IS-BRC-1215-20014)
cam.issuedOnline2022-06-06
cam.orpheus.successWed Jun 08 08:57:26 BST 2022 - Embargo updated
cam.depositDate2022-06-01
pubs.licence-identifierapollo-deposit-licence-2-1
pubs.licence-display-nameApollo Repository Deposit Licence Agreement
rioxxterms.freetoread.startdate2023-06-06


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