Gill developmental program in the teleost mandibular arch.
Published version
Peer-reviewed
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Type
Article
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Authors
Thiruppathy, Mathi https://orcid.org/0000-0002-6337-3256
Fabian, Peter
Gillis, James https://orcid.org/0000-0003-2062-3777
Crump, J Gage https://orcid.org/0000-0002-3209-0026
Abstract
Whereas no known living vertebrate possesses gills derived from the jaw-forming mandibular arch, it has been proposed that the jaw arose through modifications of an ancestral mandibular gill. Here, we show that the zebrafish pseudobranch, which regulates blood pressure in the eye, develops from mandibular arch mesenchyme and first pouch epithelia and shares gene expression, enhancer utilization, and developmental gata3 dependence with the gills. Combined with work in chondrichthyans, our findings in a teleost fish point to the presence of a mandibular pseudobranch with serial homology to gills in the last common ancestor of jawed vertebrates, consistent with a gill origin of vertebrate jaws.
Description
Keywords
Short Report, Developmental Biology, Evolutionary Biology, Pseudobranch, Gill, jaw, mandibular arch, cranial neural crest, Zebrafish
Journal Title
Elife
Conference Name
Journal ISSN
2050-084X
2050-084X
2050-084X
Volume Title
11
Publisher
eLife Sciences Publications, Ltd
Publisher DOI
Sponsorship
National Institute of Dental and Craniofacial Research (5R35DE027550)
National Institute of Dental and Craniofacial Research (5K99DE029858)
National Institute of Dental and Craniofacial Research (1F31DE030706)
Royal Society (UF130182)
Royal Society (URF\R\191007)
National Institute of Dental and Craniofacial Research (5K99DE029858)
National Institute of Dental and Craniofacial Research (1F31DE030706)
Royal Society (UF130182)
Royal Society (URF\R\191007)