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Nitrosylation rewires metabolism.

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Peer-reviewed

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Abstract

Metabolic rewiring of activated macrophages promotes glycolysis and contributes to bacterial killing. A new study shows that reactive nitrogen species, released during macrophage activation, induce a profound inhibitory signal that facilitates metabolic reprogramming by modification of lipoate.

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Journal Title

Nat Chem Biol

Conference Name

Journal ISSN

1552-4450
1552-4469

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Publisher

Springer Science and Business Media LLC

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Except where otherwised noted, this item's license is described as Attribution 4.0 International