Deadly actin collapse by disulfidptosis.
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Abstract
Programmed cell death (PCD) enables cells to co-ordinate their exit to benefit the surviving organism. A new study describes how cells can programme their death by inducing extensive disulfide bonding of the actin cytoskeleton in response to an imbalance of cystine, a raw material for glutathione production.
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Nat Cell Biol
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1465-7392
1476-4679
1476-4679
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25
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Springer Nature
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Cancer Research UK (DRCRPG-Nov22/100017)