A Flexible Multi-Sensor Device Enabling Handheld Sensing of Heart Sounds by Untrained Users.

Abstract

Heart valve disease has a large and growing burden, with a prognosis worse than many cancers. Screening with a traditional stethoscope is underutilised, often inaccurate even in skilled hands, and requires time-consuming, intimate examinations. Here, we present a handheld device to enable untrained users to record high-quality heart sounds without requiring patients to undress. The device incorporates multiple high-sensitivity sensors embedded in a flexible substrate, placed at key chest locations by the user. To address challenges from localised heart sound vibrations and noise interference, we developed time-frequency signal quality algorithms that automatically select the best sensor in the device and reject recordings with insufficient diagnostic quality. A validation study demonstrates the device's effectiveness across a diverse range of body types, with multiple sensors significantly increasing the likelihood of a successful recording. The device has the potential to enable accurate, accessible, low-cost heart disease screening.