Acknowledgements: This study makes use of de-identified data held by Our Future Health. We would like to acknowledge all the research participants who have donated their data to the Our Future Health research programme. This work uses data that has been provided by patients and collected by the NHS as part of their care and support. The data are collated, maintained, and quality assured by the National Disease Registration Service, which is part of NHS England. Access to the data was facilitated by the NHS England Data Access Request Service.