Research data supporting: "Quantification of disease-associated RNA tandem repeats by nanopore sensing"
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Description
This research data supports “Quantification of disease-associated RNA tandem repeats by nanopore sensing” which is accepted in “Nature Communications”. The data set contains the source data for each figure (Figure 1 – Figure 4) and supplementary material. LabVIEW code was used to collect and process data recorded using Axopatch 200B amplifier.
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Software / Usage instructions
Source data is presented in a .xlsx file with all values required to reproduce the datasets. The file also includes the raw PAGE and Agarose gels.
Excel, Origin Pro or Python can be used to analyse the data. Agarose and PAGE gels are included and they can be analysed in ImageJ.
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Except where otherwised noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)
Sponsorship
G.P.-G. acknowledges funding from EPSRC CDT MRes/PhD Studentship in Nanoscience and Nanotechnology (NanoDTC Cambridge EP/S022953/1) and Trinity-Henry Barlow Scholarship. U.F.K. acknowledges funding from UK Research and Innovation (UKRI) under the UK government’s Horizon Europe funding guarantee EP/ X023311/1, European Research Council (ERC) consolidator grant (DesignerPores no. 647144), an ERC-2019-PoC grant (PoreDetect no. 899538) and European Union under the Horizon 2020 Program, FET- Open: DNA-FAIRYLIGHTS, Grant Agreement No. 964995. F.B. acknowledges funding from the George and Lilian Schiff Foundation Studentship, the Winton Program for the Physics of Sustainability PhD Scholarship, and St John’s College Benefactors’ Scholarship. J.P., M.P., A.N. and D.S.-P. acknowledge support by grants from the Science Fund of the Republic of Serbia, Grant number #7754217, Understanding repeat expansion dynamics and phenotype variability in myotonic dystrophy type 1 through human studies, nanopore sequencing and cell models – READ-DM1. M. E. acknowledges funding from the European Union under the Horizon 2020 Program, FET-Open: DNA-FAIRYLIGHTS, Grant Ahorigreement No. 964995. S.P. acknowledges funding from EPSRC CDT MRes/PhD Studentship in Nanoscience and Nanotechnology (NanoDTC Cambridge EP/S022953/1).