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The Vascular Impairment of Cognition Classification Consensus Study.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Skrobot, Olivia A 
Black, Sandra 
Chen, Christopher 
DeCarli, Charles 

Abstract

INTRODUCTION: Numerous diagnostic criteria have tried to tackle the variability in clinical manifestations and problematic diagnosis of vascular cognitive impairment (VCI) but none have been universally accepted. These criteria have not been readily comparable, impacting on clinical diagnosis rates and in turn prevalence estimates, research, and treatment. METHODS: The Vascular Impairment of Cognition Classification Consensus Study (VICCCS) involved participants (81% academic researchers) from 27 countries in an online Delphi consensus study. Participants reviewed previously proposed concepts to develop new guidelines. RESULTS: VICCCS had a mean of 122 (98-153) respondents across the study and a 67% threshold to represent consensus. VICCCS redefined VCI including classification of mild and major forms of VCI and subtypes. It proposes new standardized VCI-associated terminology and future research priorities to address gaps in current knowledge. DISCUSSION: VICCCS proposes a consensus-based updated conceptualization of VCI intended to facilitate standardization in research.

Description

Keywords

Consensus, Criteria, Delphi, Guidelines, Vascular cognitive impairment, Vascular dementia, Cerebrovascular Disorders, Cognitive Dysfunction, Delphi Technique, Internet

Journal Title

Alzheimers Dement

Conference Name

Journal ISSN

1552-5260
1552-5279

Volume Title

13

Publisher

Wiley
Sponsorship
Cambridge University Hospitals NHS Foundation Trust (CUH) (unknown)
Alzheimer’s Society (UK)(Ref117)