The JAK-STAT signaling pathway is differentially activated in CALR-positive compared with JAK2V617F-positive ET patients.

The JAK-STAT signaling pathway is differentially activated in CALR-positive compared with JAK2V617F-positive ET patients.

Repository URI

https://www.repository.cam.ac.uk/handle/1810/254339

Files

HEFCE Exception sheet.pdf (86.94 KB)

Type

Authors

Lau, Winnie WY

https://orcid.org/0000-0003-1209-1854

Hannah, Rebecca

Green, Anthony R

Göttgens, Bertie

https://orcid.org/0000-0001-6302-5705

Keywords

Amino Acid Substitution, Calreticulin, Gene Ontology, Humans, Janus Kinase 2, Megakaryocytes, Mutant Proteins, Mutation, STAT Transcription Factors, Signal Transduction, Thrombocythemia, Essential

Journal Title

Blood

Journal ISSN

0006-4971
1528-0020

Volume Title

125

Publisher

American Society of Hematology

Publisher DOI

https://doi.org/10.1182/blood-2014-12-618074

Rights and licensing

All rights reserved

Except where otherwised noted, this item's license is described as All rights reserved

Sponsorship

Cancer Research Uk (None)
Biotechnology and Biological Sciences Research Council (BB/I00050X/1)
Leukaemia & Lymphoma Research (12029)
Wellcome Trust (097922/Z/11/Z)
Medical Research Council (MC_PC_12009)
Leukemia & Lymphoma Society (7001-12)
Wellcome Trust (097922/Z/11/B)
Wellcome Trust (097922/B/11/Z)

Collections

Scholarly Works - Wellcome-MRC Cambridge Stem Cell Institute
Symplectic mapped items for data match