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Should patients requiring radiotherapy for breast cancer be treated with proton beam therapy?

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Kirby, Anna M 
Holt, Francesca 
Taylor, Carolyn W 
Haviland, Joanne S 
MacKenzie, Mairead 

Abstract

Proton beam therapy is a type of radiation therapy that uses protons (high energy charged particles) rather than standard x ray radiotherapy, to treat cancer.

There are no randomised trial data supporting the routine use of proton beam therapy in patients with breast cancer, however the treatment can be more accurately targeted than x rays, potentially reducing risks of side effects in organs such as the heart.

A small cohort of breast cancer patients has a higher-than-average lifetime risk of radiation induced heart disease, and may benefit from proton beam therapy.

Description

Keywords

Humans, Female, Proton Therapy, Breast Neoplasms, Radiotherapy Dosage, Radiotherapy, Intensity-Modulated

Journal Title

BMJ

Conference Name

Journal ISSN

0959-8146
1756-1833

Volume Title

381

Publisher

BMJ