Can circulating microRNAs solve clinical dilemmas in testicular germ cell malignancy?
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Coleman, Nicholas
Abstract
Current clinical issues in testicular germ cell tumour management include limited sensitivity and specificity of conventional biomarkers and, therefore, reliance on serial CT imaging in follow-up monitoring, as well as poor ability to risk stratify patients. Circulating microRNAs are likely to help overcome these challenges and, importantly, could offer cost savings to healthcare systems.
Description
Keywords
Circulating MicroRNA, Humans, Male, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms
Journal Title
Nat Rev Urol
Conference Name
Journal ISSN
1759-4812
1759-4820
1759-4820
Volume Title
16
Publisher
Springer Science and Business Media LLC
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Rights
All rights reserved
Sponsorship
Isaac Newton Trust (1540 (f))
St Baldrick's Foundation (via Dana-Farber Cancer Institute) (2015-0743)
St Baldrick's Foundation (via Dana-Farber Cancer Institute) (2015-0743)
The authors thank St. Baldrick’s Foundation (reference 358099) and the Isaac Newton Trust (reference 15.40f) for grant funding and are grateful for support from the Max Williamson Fund and from Christiane and Alan Hodson, in memory of their daughter Olivia.