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PBP2a substitutions linked to ceftaroline resistance in MRSA isolates from the UK.

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Harrison, Ewan M 
Blane, Beth 
Ellington, Matthew J 
Loeffler, Anette 



Amino Acid Substitution, Animals, Anti-Bacterial Agents, Bacterial Proteins, Cephalosporins, Humans, Methicillin-Resistant Staphylococcus aureus, Microbial Sensitivity Tests, Penicillin-Binding Proteins, Staphylococcal Infections, United Kingdom, beta-Lactam Resistance, Ceftaroline

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J Antimicrob Chemother

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Oxford University Press (OUP)
Medical Research Council (G1000803)
Medical Research Council (G1001787)
Medical Research Council (MR/P007201/1)
Medical Research Council (G1000803/1)
Medical Research Council (G1001787/1)
This work was supported by UKCRC Translational Infection Research (TIR) Initiative, and the Medical Research Council (Grant Number G1000803) with contributions to the Grant from the Biotechnology and Biological Sciences Research Council, the National Institute for Health Research on behalf of the Department of Health, and the Chief Scientist Office of the Scottish Government Health Directorate and by a Medical Research Council Partnership grant (G1001787/1) held between the Department of Veterinary Medicine, University of Cambridge (M.A.H.), the School of Clinical Medicine, University of Cambridge (S.J.P.), the Moredun Research Institute and the Wellcome Trust Sanger Institute.