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Frail by different measures: a comparison of 8-year mortality in The Irish Longitudinal Study on Ageing (TILDA).

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Romero-Ortuno, Roman  ORCID logo
Hartley, Peter 
Kenny, Rose Anne 
O'Halloran, Aisling M 


PURPOSE: We compared the ability of four frailty identification tools (frailty phenotype: FP; FRAIL scale; 32-item Frailty Index: FI; and Clinical Frailty Scale: CFS) to predict 8-year mortality in TILDA. METHODS: We included wave 1 (2010) participants with data for all four tools. Mortality was ascertained at wave 5 (2018). Age, sex and education-adjusted binary logistic regression models were computed. RESULTS: At baseline, there were 5700 participants (mean age 63, range 50-98, 54% women). Frailty prevalences were 2.3% by FRAIL, 3.8% by FP, 10.9% by CFS, and 12.8% by FI. Mortality was 41.2%, 44.9%, 25.3% and 27.0%, respectively. The highest adjusted OR for mortality was for FRAIL (OR 4.48, 95% CI 2.93-6.85, P < 0.001), followed by FP (OR 3.55, 95% CI 2.52-5.00, P < 0.001), FI (OR 2.10, 95% CI 1.68-2.62, P < 0.001), and CFS (OR 1.88, 95% CI 1.48-2.38, P < 0.001). CONCLUSIONS: All tools significantly predicted mortality, but FRAIL and FP seemed more specific.



Comparative study, Frailty, Longitudinal study, Mortality, Older people, Aged, Aging, Female, Frail Elderly, Frailty, Geriatric Assessment, Humans, Longitudinal Studies, Male

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Springer Science and Business Media LLC
Science Foundation Ireland (18/FRL/6188)