ComplexViewer: visualization of curated macromolecular complexes.


Type
Article
Change log
Authors
Combe, Colin W 
Sivade, Marine Dumousseau 
Hermjakob, Henning 
Heimbach, Joshua 
Meldal, Birgit HM 
Abstract

SUMMARY: Proteins frequently function as parts of complexes, assemblages of multiple proteins and other biomolecules, yet network visualizations usually only show proteins as parts of binary interactions. ComplexViewer visualizes interactions with more than two participants and thereby avoids the need to first expand these into multiple binary interactions. Furthermore, if binding regions between molecules are known then these can be displayed in the context of the larger complex. AVAILABILITY AND IMPLEMENTATION: freely available under Apache version 2 license; EMBL-EBI Complex Portal: http://www.ebi.ac.uk/complexportal; Source code: https://github.com/MICommunity/ComplexViewer; Package: https://www.npmjs.com/package/complexviewer; http://biojs.io/d/complexviewer. Language: JavaScript; Web technology: Scalable Vector Graphics; Libraries: D3.js. CONTACT: colin.combe@ed.ac.uk or juri.rappsilber@ed.ac.uk.

Description
Keywords
Computational Biology, Macromolecular Substances, Models, Biological, Protein Binding, Protein Interaction Domains and Motifs, Protein Interaction Maps, Software
Journal Title
Bioinformatics
Conference Name
Journal ISSN
1367-4803
1367-4811
Volume Title
33
Publisher
Oxford University Press (OUP)
Sponsorship
BBSRC (via European Molecular Biology Laboratory (EMBL)) (CID:1861-MIDAS)