A 3D cell shape that enables tube formation.


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Article
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Authors
Abstract

Sheets of cells called epithelia can curve into tubes in embryos. Modelling and in vivo observations reveal that cells in the tube adopt an asymmetric cell shape dubbed scutoid, contrary to some previous assumptions.

Description
Keywords
Biophysics, Developmental biology, Cell Shape, Epithelium, Histone Deacetylase Inhibitors, Morphogenesis
Journal Title
Nature
Conference Name
Journal ISSN
0028-0836
1476-4687
Volume Title
561
Publisher
Springer Science and Business Media LLC
Sponsorship
Wellcome Trust (099234/Z/12/Z)
Isaac Newton Trust (Minute 1523(k))