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vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy

Accepted version
Peer-reviewed

Repository URI

https://www.repository.cam.ac.uk/handle/1810/309904

Repository DOI

https://doi.org/10.17863/CAM.57004
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Accepted version (195.76 KB)

Type

Article

Change log

Authors

Needham, Lisa-Maria  ORCID logo  https://orcid.org/0000-0002-8139-5862

Abstract

vLume, is a Virtual Reality (VR) software package designed to render large 3D Single-molecule Localization Microscopy datasets. vLume features include visualization; segmentation; bespoke analysis on complex local geometries; and exporting features. vLume can perform complex analysis on real 3D biological samples that would otherwise be impossible by using regular flat screen visualization programs.

Description

Keywords

Algorithms, Animals, COS Cells, Caulobacter crescentus, Cell Line, Cell Membrane, Chlorocebus aethiops, Clathrin, Humans, Image Processing, Computer-Assisted, Jurkat Cells, Microtubules, Nuclear Pore, Single Molecule Imaging, Software, Virtual Reality

Journal Title

Nature Methods

Conference Name

Journal ISSN

1548-7091
1548-7105

Volume Title

17

Publisher

Nature Research

Publisher DOI

https://doi.org/10.1038/s41592-020-0962-1

Rights and licensing

All rights reserved
Except where otherwised noted, this item's license is described as All rights reserved
Sponsorship
Engineering and Physical Sciences Research Council (EP/M003663/1)
The Royal Society (uf120277)
Royal Society (URF\R\180029)
Royal Society (RGF\EA\181021)
Engineering and Physical Sciences Research Council (EP/N509620/1)
Wellcome Trust (via University of Oxford) (207547/Z/17/Z)
RS URF, EPSRC Doctoral training awards, EPSRC follow on fund

Relationships

Is derived from:
https://doi.org/10.1101/2020.01.20.912733

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University of Cambridge Research Outputs (Articles and Conferences)