MACiE: a database of enzyme reaction mechanisms.
Change log
Authors
Holliday, Gemma L
Bartlett, Gail J
Almonacid, Daniel E
O'Boyle, Noel M
Murray-Rust, Peter
Abstract
SUMMARY: MACiE (mechanism, annotation and classification in enzymes) is a publicly available web-based database, held in CMLReact (an XML application), that aims to help our understanding of the evolution of enzyme catalytic mechanisms and also to create a classification system which reflects the actual chemical mechanism (catalytic steps) of an enzyme reaction, not only the overall reaction. AVAILABILITY: http://www-mitchell.ch.cam.ac.uk/macie/.
Description
Keywords
Catalysis, Computational Biology, Database Management Systems, Databases, Factual, Databases, Genetic, Databases, Protein, Enzymes, Gene Expression, Information Storage and Retrieval, Internet, Models, Chemical, Models, Statistical, Programming Languages, Proteins, Sequence Alignment, Sequence Analysis, Software
Journal Title
Bioinformatics
Conference Name
Journal ISSN
1367-4803
1460-2059
1460-2059
Volume Title
Publisher
Oxford University Press (OUP)
Publisher DOI
Sponsorship
EPSRC (G.L.H. and J.B.O.M.), the BBSRC (G.J.B. and J.M.T.—CASE studentship in association with Roche Products Ltd; N.M.O.B. and J.B.O.M.—grant BB/C51320X/1), the Chilean Government’s Ministerio de Planificacio´n y Cooperacio´n and
Cambridge Overseas Trust (D.E.A.) for funding and Unilever for supporting the Centre for Molecular Science Informatics.