A guide to naming human non-coding RNA genes.
Published version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Seal, Ruth L https://orcid.org/0000-0002-7545-6817
Chen, Ling-Ling
Griffiths-Jones, Sam
Lowe, Todd M
Mathews, Michael B
Abstract
Research on non-coding RNA (ncRNA) is a rapidly expanding field. Providing an official gene symbol and name to ncRNA genes brings order to otherwise potential chaos as it allows unambiguous communication about each gene. The HUGO Gene Nomenclature Committee (HGNC, www.genenames.org) is the only group with the authority to approve symbols for human genes. The HGNC works with specialist advisors for different classes of ncRNA to ensure that ncRNA nomenclature is accurate and informative, where possible. Here, we review each major class of ncRNA that is currently annotated in the human genome and describe how each class is assigned a standardised nomenclature.
Description
Keywords
non-coding RNA, Gene Nomenclature, Gene Symbols
Journal Title
The EMBO journal
Conference Name
Journal ISSN
0261-4189
Volume Title
39
Publisher
Publisher DOI
Sponsorship
HHS|NIH|National Human Genome Research Institute (NHGRI) (U24HG003345)
NHGRI NIH HHS (U24 HG003345)
Biotechnology and Biological Sciences Research Council (BB/M011275/1)
Wellcome Trust (208349/Z/17/Z)
NHGRI NIH HHS (U24 HG003345)
Biotechnology and Biological Sciences Research Council (BB/M011275/1)
Wellcome Trust (208349/Z/17/Z)