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dc.contributor.authorLoutsios, Chrystalla
dc.contributor.authorFarahi, Neda
dc.contributor.authorSimmonds, Rosalind
dc.contributor.authorCullum, Ian
dc.contributor.authorGillett, Daniel
dc.contributor.authorSolanki, Chandra
dc.contributor.authorSolanki, Kishor
dc.contributor.authorBuscombe, John
dc.contributor.authorCondliffe, Alison M.
dc.contributor.authorPeters, A. Mike
dc.contributor.authorChilvers, Edwin R.
dc.date.accessioned2015-11-19T16:59:35Z
dc.date.available2015-11-19T16:59:35Z
dc.date.issued2015-06-24
dc.identifier.citationLoutsios et al. Thorax (2015) Vol. 70, pp. 1085-1086. doi: 10.1136/thoraxjnl-2015-207156en
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/252661
dc.descriptionThis is the final version of the article. It first appeared from the BMJ Group via http://dx.doi.org/10.1136/thoraxjnl-2015-207156en
dc.description.abstractThe detection of focal eosinophilic inflammation by non-invasive means may aid the diagnosis and follow-up of a variety of pulmonary pathologies. All current methods of detection involve invasive sampling, which may be contraindicated or too high-risk to be performed safely. The use of injected autologous technetium-99m (Tc-99m)-labelled eosinophils coupled to single-photon emission computed tomography (SPECT) has been demonstrated to localise eosinophilic inflammation in the lungs of a patient with antineutrophil cytoplasmic antibody-positive vasculitis. Here, we report on the utility of this technique to detect active eosinophilic inflammation in a patient with focal lung inflammation where a biopsy was contraindicated.en
dc.description.sponsorshipThis work was supported by Asthma-UK (08/11), the Medical Research Council (grant number MR/J00345X/1), the Wellcome Trust (grant number 098351/Z/12/Z), and Cambridge NIHR Biomedical Research Centre.en
dc.language.isoenen
dc.publisherBMJ Groupen
dc.rightsAttribution 2.0 UK: England & Wales*
dc.rights.urihttp://creativecommons.org/licenses/by/2.0/uk/*
dc.titleClinical application of autologous technetium-99m-labelled eosinophils to detect focal eosinophilic inflammation in the lungen
dc.typeArticleen
dc.type.versionpublished versionen
prism.endingPage1086
prism.publicationDate2015
prism.publicationNameThorax
prism.startingPage1085
prism.volume70
dc.rioxxterms.funderMRC
dc.rioxxterms.funderWellcome Trust
dc.rioxxterms.funderNIHR
dc.rioxxterms.projectidMR/J00345X/1
dc.rioxxterms.projectid098351/Z/12/Z
rioxxterms.versionofrecord10.1136/thoraxjnl-2015-207156


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Attribution 2.0 UK: England & Wales
Except where otherwise noted, this item's licence is described as Attribution 2.0 UK: England & Wales