Program Synthesis Meets Deep Learning for Decoding Regulatory Networks
Current Opinion in Systems Biology
MetadataShow full item record
Fisher, J., & Woodhouse, S. (2017). Program Synthesis Meets Deep Learning for Decoding Regulatory Networks. Current Opinion in Systems Biology, 4 64-70. https://doi.org/10.1016/j.coisb.2017.07.006
With ever growing data sets spanning DNA sequencing all the way to single-cell transcriptomics, we are now facing the question of how can we turn this vast amount of information into knowledge. How do we integrate these large data sets into a coherent whole to help understand biological programs? The last few years have seen a growing interest in machine learning methods to analyse patterns in high-throughput data sets and an increasing interest in using program synthesis techniques to reconstruct and analyse executable models of gene regulatory networks. In this review, we discuss the synergies between the two methods and share our views on how they can be combined to reconstruct executable mechanistic programs directly from large-scale genomic data.
External DOI: https://doi.org/10.1016/j.coisb.2017.07.006
This record's URL: https://www.repository.cam.ac.uk/handle/1810/265695