Show simple item record

dc.contributor.authorBruford, Elspeth
dc.contributor.authorAntonescu, Cristina R
dc.contributor.authorCarroll, Andrew J
dc.contributor.authorChinnaiyan, Arul
dc.contributor.authorCree, Ian A
dc.contributor.authorCross, Nicholas CP
dc.contributor.authorDalgleish, Raymond
dc.contributor.authorGale, Robert Peter
dc.contributor.authorHarrison, Christine J
dc.contributor.authorHastings, Rosalind J
dc.contributor.authorHuret, Jean-Loup
dc.contributor.authorJohansson, Bertil
dc.contributor.authorLe Beau, Michelle
dc.contributor.authorMecucci, Cristina
dc.contributor.authorMertens, Fredrik
dc.contributor.authorVerhaak, Roel
dc.contributor.authorMitelman, Felix
dc.date.accessioned2021-10-28T08:09:16Z
dc.date.available2021-10-28T08:09:16Z
dc.date.issued2021-11
dc.date.submitted2021-09-08
dc.identifier.issn0887-6924
dc.identifier.others41375-021-01436-6
dc.identifier.other1436
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/329990
dc.description.abstractGene fusions have been discussed in the scientific literature since they were first detected in cancer cells in the early 1980s. There is currently no standardized way to denote the genes involved in fusions, but in the majority of publications the gene symbols in question are listed either separated by a hyphen (-) or by a forward slash (/). Both types of designation suffer from important shortcomings. HGNC has worked with the scientific community to determine a new, instantly recognizable and unique separator-a double colon (::)-to be used in the description of fusion genes, and advocates its usage in all databases and articles describing gene fusions.
dc.languageen
dc.publisherSpringer Science and Business Media LLC
dc.subjectConsensus Statement
dc.subject/631/208/68
dc.subject/631/208/2489/1381/1853
dc.subject/631/67/68
dc.subject/631/208/2489/68
dc.subject/631/208/69
dc.subject/45
dc.subjectconsensus-statement
dc.titleHUGO Gene Nomenclature Committee (HGNC) recommendations for the designation of gene fusions.
dc.typeOther
dc.date.updated2021-10-28T08:09:16Z
prism.endingPage3043
prism.issueIdentifier11
prism.publicationNameLeukemia
prism.startingPage3040
prism.volume35
dc.identifier.doi10.17863/CAM.77434
dcterms.dateAccepted2021-09-21
rioxxterms.versionofrecord10.1038/s41375-021-01436-6
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidBruford, Elspeth [0000-0002-8380-5247]
dc.contributor.orcidCarroll, Andrew J [0000-0001-9844-730X]
dc.contributor.orcidCross, Nicholas CP [0000-0001-5481-2555]
dc.contributor.orcidDalgleish, Raymond [0000-0001-7667-187X]
dc.contributor.orcidGale, Robert Peter [0000-0002-9156-1676]
dc.contributor.orcidMecucci, Cristina [0000-0002-1623-0148]
dc.contributor.orcidVerhaak, Roel [0000-0003-2773-0436]
dc.identifier.eissn1476-5551
pubs.funder-project-idWellcome Trust (Wellcome) (208349/Z/17/Z)
pubs.funder-project-idU.S. Department of Health & Human Services | National Institutes of Health (NIH) (U24HG003345)
cam.issuedOnline2021-10-06


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record