Clinical Characteristics, Treatment, and Short-Term Outcome in Patients with Heart Failure and Cancer.
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Piotrowski, J., Timler, M., Kozłowski, R., Stasiak, A., Stasiak, J., Bissinger, A., Timler, D., et al. (2021). Clinical Characteristics, Treatment, and Short-Term Outcome in Patients with Heart Failure and Cancer.. Clin Pract, 11 (4), 933-941. https://doi.org/10.3390/clinpract11040107
(1) Our study aimed to look at the clinical characteristics, treatment and short-term outcomes of patients hospitalized due to heart failure with coexisting cancer. (2) Methods: Seventy one cancer (Ca) patients and a randomly selected 70 patients without Ca, hospitalized due to heart failure exacerbation in the same time period constituted the study group (Ca patient group) and controls (non-Ca group), respectively. Data on clinical characteristics were collected retrospectively for both groups. (3) Results: Cancer patients presented with a less advanced NYHA class, had more frequent HFpEF, a higher peak troponin T level, and smaller left atrium size, as compared with controls. The in-hospital deaths of Ca patients were associated with: a higher New York Heart Association (NYHA) class, lower HgB level, worse renal function, higher K and AST levels, presence of diabetes mellitus, and HFpEF. By multivariate logistic regression analysis, impaired renal function was the only independent predictor of in-hospital death in Ca patients (OR-1.15; CI 1.05; 1.27); p = 0.017). The following covariates entered the regression: NYHA class, HgB, GFR, K+, AST, diabetes mellitus t.2, and HFpEF. (4) Conclusions: The clinical picture and the course of heart failure in patients with and without cancer are different.
cancer, heart failure, treatment, short-term outcome
External DOI: https://doi.org/10.3390/clinpract11040107
This record's URL: https://www.repository.cam.ac.uk/handle/1810/331807